Hurrem Sultan ,  Roxelana, was  the beloved wife of  Suleiman the magnificent and one of the most celebrated empresses of the Ottoman dynasty.   She was the first royal lady to move to Topkapi Palace from the old Palace which was situated in the grounds of  present site of the Istanbul University.
Roxelana- Hurrem Sultan
Professor Leslie Peirce, "power in the Ottoman empire was centred on the sultan's harem in Istanbul".

For some 130 years, the women of the Ottoman royal harem enjoyed extraordinary political influence. This unusual period during the 16th and 17th centuries – when powerful women exercised all royal prerogatives but one: leading Ottoman armies into battle – is popularly known as the 'sultanate of women'.
Four women stand out in this story, all royal concubines whose sons went on to occupy the Ottoman throne:

Hurrem, who first established residence in the imperial palace, in the early 1530s

Nurbanu, who, when she died in 1583, was described by the Venetian ambassador as 'a woman of the utmost goodness, courage and wisdom' despite the fact that she  'thwarted some while rewarding others' .

Kösem,  the 17th-century regent mother.

Turhan,  Kösem and her daughter-in-law Turhan, whose political rivalry culminated in Kösem's murder in 1651.

Political tutors:
It is not that royal women were not powerful in the Ottoman empire before or after the 'sultanate of women'. The famous Muslim world-traveller, Ibn Battuta, who visited the nascent Ottoman state in 1336, remarked that 'among the Turks and the Tatars their wives enjoy a very high position.'

From the time of the Ottoman dynasty's emergence in the 14th century, mothers of princes played a recognised role as political tutors and guardians of their sons – roles they would maintain throughout the dynasty's 600-year lifespan. In the 15th century, elder females – aunts, mothers and sisters of sultans – were often entrusted with critical diplomatic missions. For instance, the aspiring prince Cem sent his great-aunt, the Lady Selcuk, to persuade his elder brother to divide the empire between them – a mission that failed.
Roxelana Hurrem Sultan
Political power, however, was different from the prestige garnered by charitable acts. When Hurrem  moved into the imperial residence, she was breaking the rule that mothers of princes follow their sons' careers and reside with them in their provincial posts. She and the sultan Süleyman together also broke with other precedents. For instance, by bearing him four sons, Hurrem abandoned a central feature of the dynasty's reproductive policy - that a concubine cease her child-bearing career once she had borne one son.

The point here was that no prince should have to share with brothers the valuable political resources that a mother could provide. No wonder the public was suspicious of Hurrem and worried about the privileges that the sultan was bestowing on her. The Italian page Luigi Bassano reported that Süleyman 'has so astonished all his subjects that they say she has bewitched him'. 

ISTANBUL - Turkish Daily News Tuesday, February 26, 2008
Work has begun to establish “Hürrem Sultan Museum” in Ukraine's Rohatyn city. Ukrainian tourism professionals said in Kiev.
 
 
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Roxelana Rohatyn
Statue of Roxelana in downtown Rohatyn
Aimée du Buc de Rivéry - Naksh-i-Dil Haseki
Aimée du Buc de Rivéry - Naksh-i-Dil Haseki
Wife of Sultan Abdulhamid I and mother of sultan Mahmud II
A cousin of Empress Josephine, who went missing at sea at the age of eleven. There is a legend that she was captured by Barbary pirates, sold as a harem concubine, and was the same person as Naksh-i-Dil Haseki, a Valide Sultan.
She was born the daughter of wealthy French plantation owners on the Caribbean island of Martinique. After being sent to a convent school in France, she was returning home in July or August 1788 when the ship she was on vanished at sea. It is thought that the ship was attacked and taken by Barbary pirates. It has been suggested that she was enslaved and eventually sent to Constantinople as a gift to the Ottoman Sultan by the Bey of Algiers.




Kosem sultan
Valide Sultan Kadinefendi Kösem Sultan ( Mahpeyker), at one time named Anastasia. She was a favourite concubine in the harem. Started the sultanate of the women as she was so influential, a prominent lady.